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EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth

BACKGROUND: Activated protein C/endothelial protein C receptor (APC/EPCR) axis is physiologically involved in anticoagulant and cytoprotective activities in endothelial cells. Emerging evidence indicates that EPCR also plays a role in breast stemness and human tumorigenesis. Yet, its contribution to...

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Detalles Bibliográficos
Autores principales: Perurena, Naiara, Zandueta, Carolina, Martínez-Canarias, Susana, Moreno, Haritz, Vicent, Silvestre, Almeida, Ana S., Guruceaga, Elisabet, Gomis, Roger R., Santisteban, Marta, Egeblad, Mikala, Hermida, José, Lecanda, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248526/
https://www.ncbi.nlm.nih.gov/pubmed/28103946
http://dx.doi.org/10.1186/s13045-017-0399-x