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Biomarkers of extracellular matrix turnover are associated with emphysema and eosinophilic-bronchitis in COPD

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by airflow obstruction and loss of lung tissue mainly consisting of extracellular matrix (ECM). Three of the main ECM components are type I collagen, the main constituent in the interstitial matrix, type VI collagen, and elast...

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Detalles Bibliográficos
Autores principales: Bihlet, Asger Reinstrup, Karsdal, Morten Asser, Sand, Jannie Marie Bülow, Leeming, Diana Julie, Roberts, Mustimbo, White, Wendy, Bowler, Russell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248528/
https://www.ncbi.nlm.nih.gov/pubmed/28103932
http://dx.doi.org/10.1186/s12931-017-0509-x