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Comparison of different sample preparation methods for platinum determination in cultured cells by graphite furnace atomic absorption spectrometry

BACKGROUND: Platinum-based agents are widely used in chemotherapy against solid tumors and insufficient intracellular drug accumulation is one of the leading causes of platinum resistance which is associated with poor survival of tumor patients. Thus, the detection of intracellular platinum is pivot...

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Detalles Bibliográficos
Autores principales: Xiao, Man, Huang, Zaiju, Cai, Jing, Jia, Jinghui, Zhang, Yuzeng, Dong, Weihong, Wang, Zehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248575/
https://www.ncbi.nlm.nih.gov/pubmed/28123908
http://dx.doi.org/10.7717/peerj.2873