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Hepatic Expression of Adenovirus 36 E4ORF1 Improves Glycemic Control and Promotes Glucose Metabolism Through AKT Activation

Considering that impaired proximal insulin signaling is linked with diabetes, approaches that enhance glucose disposal independent of insulin signaling are attractive. In vitro data indicate that the E4ORF1 peptide derived from human adenovirus 36 (Ad36) interacts with cells from adipose tissue, ske...

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Detalles Bibliográficos
Autores principales: McMurphy, Travis B., Huang, Wei, Xiao, Run, Liu, Xianglan, Dhurandhar, Nikhil V., Cao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248996/
https://www.ncbi.nlm.nih.gov/pubmed/27903748
http://dx.doi.org/10.2337/db16-0876