Integrin-Linked Kinase Is Necessary for the Development of Diet-Induced Hepatic Insulin Resistance

The liver extracellular matrix (ECM) expands with high-fat (HF) feeding. This finding led us to address whether receptors for the ECM, integrins, are key to the development of diet-induced hepatic insulin resistance. Integrin-linked kinase (ILK) is a downstream integrin signaling molecule involved i...

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Detalles Bibliográficos
Autores principales: Williams, Ashley S., Trefts, Elijah, Lantier, Louise, Grueter, Carrie A., Bracy, Deanna P., James, Freyja D., Pozzi, Ambra, Zent, Roy, Wasserman, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248997/
https://www.ncbi.nlm.nih.gov/pubmed/27899483
http://dx.doi.org/10.2337/db16-0484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248997/
https://www.ncbi.nlm.nih.gov/pubmed/27899483
http://dx.doi.org/10.2337/db16-0484

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