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Integrin-Linked Kinase Is Necessary for the Development of Diet-Induced Hepatic Insulin Resistance

The liver extracellular matrix (ECM) expands with high-fat (HF) feeding. This finding led us to address whether receptors for the ECM, integrins, are key to the development of diet-induced hepatic insulin resistance. Integrin-linked kinase (ILK) is a downstream integrin signaling molecule involved i...

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Detalles Bibliográficos
Autores principales:	Williams, Ashley S., Trefts, Elijah, Lantier, Louise, Grueter, Carrie A., Bracy, Deanna P., James, Freyja D., Pozzi, Ambra, Zent, Roy, Wasserman, David H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2017
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248997/ https://www.ncbi.nlm.nih.gov/pubmed/27899483 http://dx.doi.org/10.2337/db16-0484

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