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Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence

BACKGROUND: In culturing normal diploid cells, senescence may either happen naturally, in the form of replicative senescence, or it may be a consequence of external challenges such as oxidative stress. Here we present a comparative analysis aimed at reconstruction of molecular cascades specific for...

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Detalles Bibliográficos
Autores principales: Kural, Kamil C., Tandon, Neetu, Skoblov, Mikhail, Kel-Margoulis, Olga V., Baranova, Ancha V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249001/
https://www.ncbi.nlm.nih.gov/pubmed/28105936
http://dx.doi.org/10.1186/s12864-016-3352-4