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Compromise or optimize? The breakpoint anti-median

BACKGROUND: The median of k≥3 genomes was originally defined to find a compromise genome indicative of a common ancestor. However, in gene order comparisons, the usual definitions based on minimizing the sum of distances to the input genomes lead to degenerate medians reflecting only one of the inpu...

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Detalles Bibliográficos
Autores principales: Larlee, Caroline Anne, Brandts, Alex, Sankoff, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249007/
https://www.ncbi.nlm.nih.gov/pubmed/28105920
http://dx.doi.org/10.1186/s12859-016-1340-y