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Compromise or optimize? The breakpoint anti-median
BACKGROUND: The median of k≥3 genomes was originally defined to find a compromise genome indicative of a common ancestor. However, in gene order comparisons, the usual definitions based on minimizing the sum of distances to the input genomes lead to degenerate medians reflecting only one of the inpu...
Autores principales: | Larlee, Caroline Anne, Brandts, Alex, Sankoff, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249007/ https://www.ncbi.nlm.nih.gov/pubmed/28105920 http://dx.doi.org/10.1186/s12859-016-1340-y |
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