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Osteopontin Affects Insulin Vesicle Localization and Ca(2+) Homeostasis in Pancreatic Beta Cells from Female Mice

Type 2 diabetic patients suffer from insulin resistance and reduced insulin secretion. Osteopontin (OPN), a versatile protein expressed in several tissues throughout the body including the islets of Langerhans, has previously been implicated in the development of insulin resistance. Here we have inv...

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Detalles Bibliográficos
Autores principales: Wendt, Anna, Mollet, Inês G., Knutsson, Anki, Bolmgren, Victor S., Hultgårdh-Nilsson, Anna, Gomez, Maria F., Eliasson, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249066/
https://www.ncbi.nlm.nih.gov/pubmed/28107503
http://dx.doi.org/10.1371/journal.pone.0170498