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Osteopontin Affects Insulin Vesicle Localization and Ca(2+) Homeostasis in Pancreatic Beta Cells from Female Mice
Type 2 diabetic patients suffer from insulin resistance and reduced insulin secretion. Osteopontin (OPN), a versatile protein expressed in several tissues throughout the body including the islets of Langerhans, has previously been implicated in the development of insulin resistance. Here we have inv...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249066/ https://www.ncbi.nlm.nih.gov/pubmed/28107503 http://dx.doi.org/10.1371/journal.pone.0170498 |