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Syk Regulates Neutrophilic Airway Hyper-Responsiveness in a Chronic Mouse Model of Allergic Airways Inflammation

BACKGROUND: Asthma is a chronic inflammatory disease characterized by airways hyper-responsiveness (AHR), reversible airway obstruction, and airway inflammation and remodeling. We previously showed that Syk modulates methacholine-induced airways contractility in naïve mice and in mice with allergic...

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Detalles Bibliográficos
Autores principales: Salehi, Sepehr, Wang, Xiaomin, Juvet, Stephen, Scott, Jeremy A., Chow, Chung-Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249072/
https://www.ncbi.nlm.nih.gov/pubmed/28107345
http://dx.doi.org/10.1371/journal.pone.0163614