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Syk Regulates Neutrophilic Airway Hyper-Responsiveness in a Chronic Mouse Model of Allergic Airways Inflammation
BACKGROUND: Asthma is a chronic inflammatory disease characterized by airways hyper-responsiveness (AHR), reversible airway obstruction, and airway inflammation and remodeling. We previously showed that Syk modulates methacholine-induced airways contractility in naïve mice and in mice with allergic...
Autores principales: | Salehi, Sepehr, Wang, Xiaomin, Juvet, Stephen, Scott, Jeremy A., Chow, Chung-Wai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249072/ https://www.ncbi.nlm.nih.gov/pubmed/28107345 http://dx.doi.org/10.1371/journal.pone.0163614 |
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