An Approach to Elucidate NBS1 Function in DNA Repair Using Frequent Nonsynonymous Polymorphism in Wild Medaka (Oryzias latipes) Populations

Nbs1 is one of the genes responsible for Nijmegen breakage syndrome, which is marked with high radiosensitivity. In human NBS1 (hNBS1), Q185E polymorphism is known as the factor to cancer risks, although its DSB repair defect has not been addressed. Here we investigated the genetic variations in med...

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Detalles Bibliográficos
Autores principales: Igarashi, Kento, Kobayashi, Junya, Katsumura, Takafumi, Urushihara, Yusuke, Hida, Kyohei, Watanabe-Asaka, Tomomi, Oota, Hiroki, Oda, Shoji, Mitani, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249114/
https://www.ncbi.nlm.nih.gov/pubmed/28107384
http://dx.doi.org/10.1371/journal.pone.0170006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249114/
https://www.ncbi.nlm.nih.gov/pubmed/28107384
http://dx.doi.org/10.1371/journal.pone.0170006

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