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The Polyherbal Wattana Formula Displays Anti-Amyloidogenic Properties by Increasing α-Secretase Activities

Alzheimer’s disease is characterized by the deposition of insoluble amyloid-β peptides produced from the β-amyloid precursor protein (βAPP). Because α-secretase cleavage by ADAM10 and ADAM17 takes place in the middle of Aβ, its activation is considered as a promising anti-AD therapeutic track. Here...

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Detalles Bibliográficos
Autores principales: Htoo, Htut Htut, Limsuvan, Suveerawan, Thamsermsang, Onusa, Hernandez, Jean-François, Checler, Frédéric, Govitrapong, Piyarat, Pakaprot, Narawut, Akarasereenont, Pravit, Vincent, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249131/
https://www.ncbi.nlm.nih.gov/pubmed/28107420
http://dx.doi.org/10.1371/journal.pone.0170360