Drosophila Vps13 Is Required for Protein Homeostasis in the Brain

Chorea-Acanthocytosis is a rare, neurodegenerative disorder characterized by progressive loss of locomotor and cognitive function. It is caused by loss of function mutations in the Vacuolar Protein Sorting 13A (VPS13A) gene, which is conserved from yeast to human. The consequences of VPS13A dysfunct...

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Detalles Bibliográficos
Autores principales: Vonk, Jan J., Yeshaw, Wondwossen M., Pinto, Francesco, Faber, Anita I. E., Lahaye, Liza L., Kanon, Bart, van der Zwaag, Marianne, Velayos-Baeza, Antonio, Freire, Raimundo, van IJzendoorn, Sven C., Grzeschik, Nicola A., Sibon, Ody C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249141/
https://www.ncbi.nlm.nih.gov/pubmed/28107480
http://dx.doi.org/10.1371/journal.pone.0170106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249141/
https://www.ncbi.nlm.nih.gov/pubmed/28107480
http://dx.doi.org/10.1371/journal.pone.0170106

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