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Drosophila Vps13 Is Required for Protein Homeostasis in the Brain
Chorea-Acanthocytosis is a rare, neurodegenerative disorder characterized by progressive loss of locomotor and cognitive function. It is caused by loss of function mutations in the Vacuolar Protein Sorting 13A (VPS13A) gene, which is conserved from yeast to human. The consequences of VPS13A dysfunct...
Autores principales: | Vonk, Jan J., Yeshaw, Wondwossen M., Pinto, Francesco, Faber, Anita I. E., Lahaye, Liza L., Kanon, Bart, van der Zwaag, Marianne, Velayos-Baeza, Antonio, Freire, Raimundo, van IJzendoorn, Sven C., Grzeschik, Nicola A., Sibon, Ody C. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249141/ https://www.ncbi.nlm.nih.gov/pubmed/28107480 http://dx.doi.org/10.1371/journal.pone.0170106 |
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