T Cell Subset and Stimulation Strength-Dependent Modulation of T Cell Activation by Kv1.3 Blockers

Kv1.3 is a voltage-gated potassium channel expressed on T cells that plays an important role in T cell activation. Previous studies have shown that blocking Kv1.3 channels in human T cells during activation results in reduced calcium entry, cytokine production, and proliferation. The aim of the pres...

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Detalles Bibliográficos
Autores principales: Fung-Leung, Wai-Ping, Edwards, Wilson, Liu, Yi, Ngo, Karen, Angsana, Julianty, Castro, Glenda, Wu, Nancy, Liu, Xuejun, Swanson, Ronald V., Wickenden, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249144/
https://www.ncbi.nlm.nih.gov/pubmed/28107393
http://dx.doi.org/10.1371/journal.pone.0170102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249144/
https://www.ncbi.nlm.nih.gov/pubmed/28107393
http://dx.doi.org/10.1371/journal.pone.0170102

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