Deficient Cholesterol Esterification in Plasma of apoc2 Knockout Zebrafish and Familial Chylomicronemia Patients

Hypertriglyceridemia is an independent risk factor for cardiovascular disease. Apolipoprotein C-II (APOC2) is an obligatory cofactor for lipoprotein lipase (LPL), the major enzyme catalyzing plasma triglyceride hydrolysis. We have created an apoc2 knockout zebrafish model, which mimics the familial...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Gaudet, Daniel, Miller, Yury I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249157/
https://www.ncbi.nlm.nih.gov/pubmed/28107429
http://dx.doi.org/10.1371/journal.pone.0169939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249157/
https://www.ncbi.nlm.nih.gov/pubmed/28107429
http://dx.doi.org/10.1371/journal.pone.0169939

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