Upon Accounting for the Impact of Isoenzyme Loss, Gene Deletion Costs Anticorrelate with Their Evolutionary Rates

System-level metabolic network models enable the computation of growth and metabolic phenotypes from an organism’s genome. In particular, flux balance approaches have been used to estimate the contribution of individual metabolic genes to organismal fitness, offering the opportunity to test whether...

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Detalles Bibliográficos
Autores principales: Jacobs, Christopher, Lambourne, Luke, Xia, Yu, Segrè, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249160/
https://www.ncbi.nlm.nih.gov/pubmed/28107392
http://dx.doi.org/10.1371/journal.pone.0170164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249160/
https://www.ncbi.nlm.nih.gov/pubmed/28107392
http://dx.doi.org/10.1371/journal.pone.0170164

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