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Impact of Donor Activating KIR Genes on HSCT Outcome in C1-Ligand Negative Myeloid Disease Patients Transplanted with Unrelated Donors—A Retrospective Study

Natural Killer cells (NK) are lymphocytes with the potential to recognize and lyse cells which escaped T-cell mediated lysis due to their aberrant HLA expression profiles. Killer cell immunoglobulin-like receptors (KIR) influence NK-cell activity by mediation of activating or inhibitory signals upon...

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Detalles Bibliográficos
Autores principales: Neuchel, Christine, Fürst, Daniel, Niederwieser, Dietger, Bunjes, Donald, Tsamadou, Chrysanthi, Wulf, Gerald, Pfreundschuh, Michael, Wagner, Eva, Stuhler, Gernot, Einsele, Hermann, Schrezenmeier, Hubert, Mytilineos, Joannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249182/
https://www.ncbi.nlm.nih.gov/pubmed/28107369
http://dx.doi.org/10.1371/journal.pone.0169512