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Impact of Donor Activating KIR Genes on HSCT Outcome in C1-Ligand Negative Myeloid Disease Patients Transplanted with Unrelated Donors—A Retrospective Study
Natural Killer cells (NK) are lymphocytes with the potential to recognize and lyse cells which escaped T-cell mediated lysis due to their aberrant HLA expression profiles. Killer cell immunoglobulin-like receptors (KIR) influence NK-cell activity by mediation of activating or inhibitory signals upon...
Autores principales: | Neuchel, Christine, Fürst, Daniel, Niederwieser, Dietger, Bunjes, Donald, Tsamadou, Chrysanthi, Wulf, Gerald, Pfreundschuh, Michael, Wagner, Eva, Stuhler, Gernot, Einsele, Hermann, Schrezenmeier, Hubert, Mytilineos, Joannis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249182/ https://www.ncbi.nlm.nih.gov/pubmed/28107369 http://dx.doi.org/10.1371/journal.pone.0169512 |
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