Nonstructural 5A Protein of Hepatitis C Virus Interferes with Toll-Like Receptor Signaling and Suppresses the Interferon Response in Mouse Liver

The hepatitis C virus nonstructural protein NS5A is involved in resistance to the host immune response, as well as the viral lifecycle such as replication and maturation. Here, we established transgenic mice expressing NS5A protein in the liver and examined innate immune responses against lipopolysa...

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Detalles Bibliográficos
Autores principales: Tsutsumi, Takeya, Okushin, Kazuya, Enooku, Kenichiro, Fujinaga, Hidetaka, Moriya, Kyoji, Yotsuyanagi, Hiroshi, Aizaki, Hideki, Suzuki, Tetsuro, Matsuura, Yoshiharu, Koike, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249188/
https://www.ncbi.nlm.nih.gov/pubmed/28107512
http://dx.doi.org/10.1371/journal.pone.0170461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249188/
https://www.ncbi.nlm.nih.gov/pubmed/28107512
http://dx.doi.org/10.1371/journal.pone.0170461

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