Periostin regulates fibrocyte function to promote myofibroblast differentiation and lung fibrosis

Fibrocytes are circulating mesenchymal precursors (CD45+, col 1+) recruited to fibrotic areas. Fibrocytes secrete profibrotic mediators including periostin; a matricellular protein that regulates cellular interactions with extracellular matrix (ECM) components. In bleomycin-induced fibrosis, periost...

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Detalles Bibliográficos
Autores principales: Ashley, Shanna L., Wilke, Carol A., Kim, Kevin K., Moore, Bethany B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250615/
https://www.ncbi.nlm.nih.gov/pubmed/27435108
http://dx.doi.org/10.1038/mi.2016.61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250615/
https://www.ncbi.nlm.nih.gov/pubmed/27435108
http://dx.doi.org/10.1038/mi.2016.61

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