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S2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands

BACKGROUND: Sigma (σ) receptors are accepted as a particular receptor class consisting of two subtypes: sigma-1 (σ(1)) and sigma-2 (σ(2)). The two receptor subtypes have specific drug actions, pharmacological profiles and molecular characteristics. The σ(2) receptor is overexpressed in several tumor...

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Detalles Bibliográficos
Autores principales: Nastasi, Giovanni, Miceli, Carla, Pittalà, Valeria, Modica, Maria N., Prezzavento, Orazio, Romeo, Giuseppe, Rescifina, Antonio, Marrazzo, Agostino, Amata, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250622/
https://www.ncbi.nlm.nih.gov/pubmed/28123452
http://dx.doi.org/10.1186/s13321-017-0191-5