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PI3K and MAPK pathways mediate the BDNF/TrkB-increased metastasis in neuroblastoma
Brain-derived neurotrophic factor (BDNF) and its tyrosine kinase receptor TrkB have been reported to be associated with poor prognosis in neuroblastoma (NB) patients. Our previous studies indicated that BDNF activation of TrkB induces chemo-resistance through activation of phosphoinositide-3-kinase...
Autores principales: | Hua, Zhongyan, Gu, Xiao, Dong, Yudi, Tan, Fei, Liu, Zhihui, Thiele, Carol J., Li, Zhijie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250655/ https://www.ncbi.nlm.nih.gov/pubmed/27752996 http://dx.doi.org/10.1007/s13277-016-5433-z |
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