Gastrin activates autophagy and increases migration and survival of gastric adenocarcinoma cells

BACKGROUND: The peptide hormone gastrin exerts a growth-promoting effect in both normal and malignant gastrointestinal tissue. Gastrin mediates its effect via the cholecystokinin 2 receptor (CCKBR/CCK2R). Although a substantial part of the gastric adenocarcinomas express gastrin and CCKBR, the role...

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Detalles Bibliográficos
Autores principales: Rao, Shalini V., Solum, Guri, Niederdorfer, Barbara, Nørsett, Kristin G., Bjørkøy, Geir, Thommesen, Liv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251222/
https://www.ncbi.nlm.nih.gov/pubmed/28109268
http://dx.doi.org/10.1186/s12885-017-3055-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251222/
https://www.ncbi.nlm.nih.gov/pubmed/28109268
http://dx.doi.org/10.1186/s12885-017-3055-5

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