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Gastrin activates autophagy and increases migration and survival of gastric adenocarcinoma cells

BACKGROUND: The peptide hormone gastrin exerts a growth-promoting effect in both normal and malignant gastrointestinal tissue. Gastrin mediates its effect via the cholecystokinin 2 receptor (CCKBR/CCK2R). Although a substantial part of the gastric adenocarcinomas express gastrin and CCKBR, the role...

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Detalles Bibliográficos
Autores principales:	Rao, Shalini V., Solum, Guri, Niederdorfer, Barbara, Nørsett, Kristin G., Bjørkøy, Geir, Thommesen, Liv
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251222/ https://www.ncbi.nlm.nih.gov/pubmed/28109268 http://dx.doi.org/10.1186/s12885-017-3055-5

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