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Blocking of platelet glycoprotein receptor Ib reduces “thrombo-inflammation” in mice with acute ischemic stroke

BACKGROUND: Ischemic stroke causes a strong inflammatory response that includes T cells, monocytes/macrophages, and neutrophils. Interaction of these immune cells with platelets and endothelial cells facilitates microvascular dysfunction and leads to secondary infarct growth. We recently showed that...

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Detalles Bibliográficos
Autores principales: Schuhmann, Michael K., Guthmann, Josua, Stoll, Guido, Nieswandt, Bernhard, Kraft, Peter, Kleinschnitz, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251224/
https://www.ncbi.nlm.nih.gov/pubmed/28109273
http://dx.doi.org/10.1186/s12974-017-0792-y