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Blocking of platelet glycoprotein receptor Ib reduces “thrombo-inflammation” in mice with acute ischemic stroke
BACKGROUND: Ischemic stroke causes a strong inflammatory response that includes T cells, monocytes/macrophages, and neutrophils. Interaction of these immune cells with platelets and endothelial cells facilitates microvascular dysfunction and leads to secondary infarct growth. We recently showed that...
Autores principales: | Schuhmann, Michael K., Guthmann, Josua, Stoll, Guido, Nieswandt, Bernhard, Kraft, Peter, Kleinschnitz, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251224/ https://www.ncbi.nlm.nih.gov/pubmed/28109273 http://dx.doi.org/10.1186/s12974-017-0792-y |
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