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A randomised, active- and placebo-controlled, three-period crossover trial to investigate short-term effects of the dipeptidyl peptidase-4 inhibitor linagliptin on macro- and microvascular endothelial function in type 2 diabetes

BACKGROUND: Studies of dipeptidyl peptidase (DPP)-4 inhibitors report heterogeneous effects on endothelial function in patients with type 2 diabetes (T2D). This study assessed the effects of the DPP-4 inhibitor linagliptin versus the sulphonylurea glimepiride and placebo on measures of macro- and mi...

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Detalles Bibliográficos
Autores principales: Jax, Thomas, Stirban, Alin, Terjung, Arne, Esmaeili, Habib, Berk, Andreas, Thiemann, Sandra, Chilton, Robert, von Eynatten, Maximilian, Marx, Nikolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251248/
https://www.ncbi.nlm.nih.gov/pubmed/28109295
http://dx.doi.org/10.1186/s12933-016-0493-3