Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties

BACKGROUND: PPARγ is an isoform of peroxisome proliferator-activated receptor (PPAR) belonging to a super family of nuclear receptors. PPARγ receptor is found to play a crucial role in the modulation of lipid and glucose homeostasis. Its commotion has been reported to play a significant role in a br...

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Detalles Bibliográficos
Autores principales: Muralikumar, Shalini, Vetrivel, Umashankar, Narayanasamy, Angayarkanni, N. Das, Undurti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251316/
https://www.ncbi.nlm.nih.gov/pubmed/28109294
http://dx.doi.org/10.1186/s12944-016-0404-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251316/
https://www.ncbi.nlm.nih.gov/pubmed/28109294
http://dx.doi.org/10.1186/s12944-016-0404-3

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