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Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis

BACKGROUND: Osteosarcoma (OS) is the most common primary bone tumor in both humans and dogs and is the second leading cause of cancer related deaths in children and young adults. Limb sparing surgery along with chemotherapy has been the mainstay of treatment for OS. Many patients are not cured with...

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Detalles Bibliográficos
Autores principales: Murahari, Sridhar, Jalkanen, Aimee L., Kulp, Samuel K., Chen, Ching-Shih, Modiano, Jaime F., London, Cheryl A., Kisseberth, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251323/
https://www.ncbi.nlm.nih.gov/pubmed/28109246
http://dx.doi.org/10.1186/s12885-017-3046-6