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Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis
BACKGROUND: Osteosarcoma (OS) is the most common primary bone tumor in both humans and dogs and is the second leading cause of cancer related deaths in children and young adults. Limb sparing surgery along with chemotherapy has been the mainstay of treatment for OS. Many patients are not cured with...
Autores principales: | Murahari, Sridhar, Jalkanen, Aimee L., Kulp, Samuel K., Chen, Ching-Shih, Modiano, Jaime F., London, Cheryl A., Kisseberth, William C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251323/ https://www.ncbi.nlm.nih.gov/pubmed/28109246 http://dx.doi.org/10.1186/s12885-017-3046-6 |
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