Everolimus is better than rapamycin in attenuating neuroinflammation in kainic acid-induced seizures

BACKGROUND: Microglia is responsible for neuroinflammation, which may aggravate brain injury in diseases like epilepsy. Mammalian target of rapamycin (mTOR) kinase is related to microglial activation with subsequent neuroinflammation. In the present study, rapamycin and everolimus, both as mTOR inhi...

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Detalles Bibliográficos
Autores principales: Yang, Ming-Tao, Lin, Yi-Chin, Ho, Whae-Hong, Liu, Chao-Lin, Lee, Wang-Tso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251325/
https://www.ncbi.nlm.nih.gov/pubmed/28109197
http://dx.doi.org/10.1186/s12974-017-0797-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251325/
https://www.ncbi.nlm.nih.gov/pubmed/28109197
http://dx.doi.org/10.1186/s12974-017-0797-6

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