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Interleukin-1 as a mediator of fatigue in disease: a narrative review

Fatigue is commonly reported in a variety of illnesses, and it has major impact on quality of life. Previously, it was thought that fatigue originates in the skeletal muscles, leading to cessation of activity. However, more recently, it has become clear that the brain is the central regulator of fat...

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Detalles Bibliográficos
Autores principales: Roerink, Megan E., van der Schaaf, Marieke E., Dinarello, Charles A., Knoop, Hans, van der Meer, Jos W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251329/
https://www.ncbi.nlm.nih.gov/pubmed/28109186
http://dx.doi.org/10.1186/s12974-017-0796-7