Racemic Salsolinol and its Enantiomers Act as Agonists of the μ-Opioid Receptor by Activating the Gi Protein-Adenylate Cyclase Pathway

Background: Several studies have shown that the ethanol-derived metabolite salsolinol (SAL) can activate the mesolimbic system, suggesting that SAL is the active molecule mediating the rewarding effects of ethanol. In vitro and in vivo studies suggest that SAL exerts its action on neuron excitabilit...

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Detalles Bibliográficos
Autores principales: Berríos-Cárcamo, Pablo, Quintanilla, María E., Herrera-Marschitz, Mario, Vasiliou, Vasilis, Zapata-Torres, Gerald, Rivera-Meza, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253357/
https://www.ncbi.nlm.nih.gov/pubmed/28167903
http://dx.doi.org/10.3389/fnbeh.2016.00253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253357/
https://www.ncbi.nlm.nih.gov/pubmed/28167903
http://dx.doi.org/10.3389/fnbeh.2016.00253

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