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The plant defensin NaD1 induces tumor cell death via a non-apoptotic, membranolytic process

Cationic anti-microbial peptides (CAPs) have an important role in host innate defense against pathogens such as bacteria and fungi. Many CAPs including defensins also exhibit selective cytotoxic activity towards mammalian cells via both apoptotic and non-apoptotic processes, and are being investigat...

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Detalles Bibliográficos
Autores principales: Baxter, Amy A, Poon, Ivan KH, Hulett, Mark D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253418/
https://www.ncbi.nlm.nih.gov/pubmed/28179997
http://dx.doi.org/10.1038/cddiscovery.2016.102