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Reduction of hepatic fibrosis by overexpression of von Hippel–Lindau protein in experimental models of chronic liver disease

Hypoxia-inducible factor (HIF)-1α and HIF-2α play an important role in liver fibrosis. von Hippel–Lindau protein (VHL), a key mediator of HIF-α, regulates fibrosis in an organ- and cell-specific way. In this study, human liver samples were collected from hepatitis C-, alcoholic-, and cholestatic-ass...

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Detalles Bibliográficos
Autores principales: Wang, Jizhou, Lu, Zhaoyang, Xu, Zhilin, Tian, Pei, Miao, Hui, Pan, Shangha, Song, Ruipeng, Sun, Xueying, Zhao, Baolei, Wang, Dawei, Ma, Yong, Song, Xuan, Zhang, Shugeng, Liu, Lianxin, Jiang, Hongchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253623/
https://www.ncbi.nlm.nih.gov/pubmed/28112200
http://dx.doi.org/10.1038/srep41038