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Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification

Crosstalk between the SUMO and ubiquitin pathways has recently been reported. However, no approach currently exists to determine the interrelationship between these modifications. Here, we report an optimized immunoaffinity method that permits the study of both protein ubiquitylation and SUMOylation...

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Detalles Bibliográficos
Autores principales: Lamoliatte, Frédéric, McManus, Francis P., Maarifi, Ghizlane, Chelbi-Alix, Mounira K., Thibault, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253644/
https://www.ncbi.nlm.nih.gov/pubmed/28098164
http://dx.doi.org/10.1038/ncomms14109