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α3 Chains of type V collagen regulate breast tumour growth via glypican-1

Pericellular α3(V) collagen can affect the functioning of cells, such as adipocytes and pancreatic β cells. Here we show that α3(V) chains are an abundant product of normal mammary gland basal cells, and that α3(V) ablation in a mouse mammary tumour model inhibits mammary tumour progression by reduc...

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Detalles Bibliográficos
Autores principales: Huang, Guorui, Ge, Gaoxiang, Izzi, Valerio, Greenspan, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253704/
https://www.ncbi.nlm.nih.gov/pubmed/28102194
http://dx.doi.org/10.1038/ncomms14351