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Mincle activation enhances neutrophil migration and resistance to polymicrobial septic peritonitis

Sepsis is a systemic inflammatory response to bacterial infection. The therapeutic options for treating sepsis are limited. Impaired neutrophil recruitment into the infection site is directly associated with severe sepsis, but the precise mechanism is unclear. Here, we show that Mincle plays a key r...

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Detalles Bibliográficos
Autores principales: Lee, Wook-Bin, Yan, Ji-Jing, Kang, Ji-Seon, Zhang, Quanri, Choi, Won Young, Kim, Lark Kyun, Kim, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253726/
https://www.ncbi.nlm.nih.gov/pubmed/28112221
http://dx.doi.org/10.1038/srep41106