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Decreased expression of pseudogene PTENP1 promotes malignant behaviours and is associated with the poor survival of patients with HNSCC

PTENP1, a pseudogene of PTEN, was previously reported to be a tumour suppressor in some cancer types. However, there was no evidence for the biological function and expression of PTENP1 in head and neck squamous cell carcinoma (HNSCC). Here, we evaluated the function and clinical implications of PTE...

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Detalles Bibliográficos
Autores principales: Liu, Jiannan, Xing, Yue, Xu, Liqun, Chen, Wantao, Cao, Wei, Zhang, Chenping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255549/
https://www.ncbi.nlm.nih.gov/pubmed/28112249
http://dx.doi.org/10.1038/srep41179