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Understanding the dynamics of Toll-like Receptor 5 response to flagellin and its regulation by estradiol

Toll-like receptors (TLRs) are major players of the innate immune system. Once activated, they trigger a signalling cascade that leads to NF-κB translocation from the cytoplasm to the nucleus. Single cell analysis shows that NF-κB signalling dynamics are a critical determinant of transcriptional reg...

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Detalles Bibliográficos
Autores principales: Caballero, Ignacio, Boyd, James, Almiñana, Carmen, Sánchez-López, Javier A., Basatvat, Shaghayegh, Montazeri, Mehrnaz, Maslehat Lay, Nasim, Elliott, Sarah, Spiller, David G., White, Michael R. H., Fazeli, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256028/
https://www.ncbi.nlm.nih.gov/pubmed/28112187
http://dx.doi.org/10.1038/srep40981