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VDAC–Tubulin, an Anti-Warburg Pro-Oxidant Switch
Aerobic enhanced glycolysis characterizes the Warburg phenotype. In cancer cells, suppression of mitochondrial metabolism contributes to maintain a low ATP/ADP ratio that favors glycolysis. We propose that the voltage-dependent anion channel (VDAC) located in the mitochondrial outer membrane is a me...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256068/ https://www.ncbi.nlm.nih.gov/pubmed/28168164 http://dx.doi.org/10.3389/fonc.2017.00004 |