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Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma

3β-Hydroxysteroid-Δ24 reductase (DHCR24), the final enzyme of the cholesterol biosynthetic pathway, has been associated with urogenital neoplasms. However, the function of DHCR24 in endometrial cancer (EC) remains largely elusive. Here, we analyzed the expression profile of DHCR24 and the progestero...

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Detalles Bibliográficos
Autores principales: Dai, Miao, Zhu, Xiao-Lu, Liu, Fei, Xu, Qin-Yang, Ge, Qiu-Lin, Jiang, Shu-Heng, Yang, Xiao-Mei, Li, Jun, Wang, Ya-Hui, Wu, Qing-Kai, Ai, Zhi-Hong, Teng, Yin-Cheng, Zhang, Zhi-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256103/
https://www.ncbi.nlm.nih.gov/pubmed/28112250
http://dx.doi.org/10.1038/srep41404