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Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma
3β-Hydroxysteroid-Δ24 reductase (DHCR24), the final enzyme of the cholesterol biosynthetic pathway, has been associated with urogenital neoplasms. However, the function of DHCR24 in endometrial cancer (EC) remains largely elusive. Here, we analyzed the expression profile of DHCR24 and the progestero...
Autores principales: | Dai, Miao, Zhu, Xiao-Lu, Liu, Fei, Xu, Qin-Yang, Ge, Qiu-Lin, Jiang, Shu-Heng, Yang, Xiao-Mei, Li, Jun, Wang, Ya-Hui, Wu, Qing-Kai, Ai, Zhi-Hong, Teng, Yin-Cheng, Zhang, Zhi-Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256103/ https://www.ncbi.nlm.nih.gov/pubmed/28112250 http://dx.doi.org/10.1038/srep41404 |
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