The V‐ATPase is expressed in the choroid plexus and mediates cAMP‐induced intracellular pH alterations

The cerebrospinal fluid (CSF) pH influences brain interstitial pH and, therefore, brain function. We hypothesized that the choroid plexus epithelium (CPE) expresses the vacuolar H(+)‐ATPase (V‐ATPase) as an acid extrusion mechanism in the luminal membrane to counteract detrimental elevations in CSF...

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Detalles Bibliográficos
Autores principales: Christensen, Henriette L., Păunescu, Teodor G., Matchkov, Vladimir, Barbuskaite, Dagne, Brown, Dennis, Damkier, Helle H., Praetorius, Jeppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256157/
https://www.ncbi.nlm.nih.gov/pubmed/28053225
http://dx.doi.org/10.14814/phy2.13072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256157/
https://www.ncbi.nlm.nih.gov/pubmed/28053225
http://dx.doi.org/10.14814/phy2.13072

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