Lentiviral vector‐encoded microRNA‐based shRNA‐mediated gene knockdown of N‐methyl‐D‐aspartate receptors in skin reduces pain

BACKGROUND AND PURPOSE: RNA polymerase II promoters that drive the expression of rationally designed primary microRNA‐based shRNA, for example, shRNAmir, can produce more potent gene knockdown than RNA polymerase III promoters. Antagonists of peripheral N methyl‐D‐aspartate (NMDA) receptors that do...

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Detalles Bibliográficos
Autores principales: Liu, Chien‐Cheng, Cheng, Jiin‐Tsuey, Hung, Kuo‐Chuan, Chia, Yuan‐Yi, Tan, Ping‐Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256174/
https://www.ncbi.nlm.nih.gov/pubmed/28127509
http://dx.doi.org/10.1002/brb3.587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256174/
https://www.ncbi.nlm.nih.gov/pubmed/28127509
http://dx.doi.org/10.1002/brb3.587

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