Chlorpyrifos inhibits neural induction via Mfn1-mediated mitochondrial dysfunction in human induced pluripotent stem cells

Organophosphates, such as chlorpyrifos (CPF), are widely used as insecticides in agriculture. CPF is known to induce cytotoxicity, including neurodevelopmental toxicity. However, the molecular mechanisms of CPF toxicity at early fetal stage have not been fully elucidated. In this study, we examined...

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Detalles Bibliográficos
Autores principales: Yamada, Shigeru, Kubo, Yusuke, Yamazaki, Daiju, Sekino, Yuko, Kanda, Yasunari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256306/
https://www.ncbi.nlm.nih.gov/pubmed/28112198
http://dx.doi.org/10.1038/srep40925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256306/
https://www.ncbi.nlm.nih.gov/pubmed/28112198
http://dx.doi.org/10.1038/srep40925

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